As part of the Michigan Social Work Centennial, we are delighted to feature cutting-edge, contemporary innovations in social work practice that are being created by Michigan faculty members. This series will consist of three sessions showcasing mental health intervention research happening at the University of Michigan School of Social Work.
Featuring innovative research from SSW faculty, the session provides examples of community- and clinic-based efforts to advance health, mental health, and behavioral health outcomes in diverse communities. The program includes a focus on innovative approaches to address and overcome health disparities. An interactive panel discussion will explore the diversity and promise of current SSW research.
Jackie Hawkins – Program AACTIVE: African Americans Coming Together to Increase Vital Exercise
David Cordova – Randomized Controlled Trial of a Mobile Health App for Substance Use, Sexual Risk Behaviors, and Testing for Sexually Transmitted Infections and HIV Among Youth: 6 Month Outcomes
Brad Zebrack – Supportive Care in Cancer: Patient needs and psychosocial Intervention
Anao Zhang – Delivering an engaging and tailorable technology-based cognitive behavioral therapy for depression among adolescents and young adults diagnosed with cancer
Jamie Mitchell – Discussant
Good afternoon everybody
00:00
[Music]
good afternoon everybody i'm john
trotman henry meyer collegiate professor
of social work and co-chair of the
centennial it's my honor to welcome you
to the second of three centennial
lectures
co-occurring
health and mental health conditions as
part of our centennial celebration
we're excited to bring to you some of
the groundbreaking work of our faculty
at this point i want to turn it over
to our associate dean
to introduce the panelists
hello everyone
my name is joe hemley i'm a faculty
member here at the school of social work
and as john said the associate dean for
faculty affairs
um today's session provides examples of
community-engaged and clinic-based
research
focused on multi-level interventions to
address
co-occurring health and mental health
issues the interactive panel discussion
will explore the diversity and promise
of social work-based research
now i get to introduce our speakers
which will we'll do all together
first uh our discussion for today's
session and um
is dr jamie mitchell
jamie is associate professor of social
work and is a health disparities
researcher extensive experience
conducting research on health behaviors
health communication strategies
uh with the focus of optimizing
well-being and longevity for african
americans with a particular emphasis on
african-american men
her reach research uh focuses on older
african-american men's preventative
health behaviors
uh she has a recent nih
r 24 grant involving the recruitment and
retaining of older african americans in
research
so most recently dr mitchell has also
taken on a role as a assistant director
of the clinical research participation
of clinical research participation at
michigan medicine's robo cancer center
so
dr mitchell is our discussant our first
panelist is dr jacqueline hawkins an
assistant professor at social work in
the school social work here associate
director of the gender and health
research lab and
her dr hawkins's research agenda is
focused on social determinants of health
behavior in african americans and
latinos
with diabetes she's particularly
interested in factors that contribute to
and
to contribute to excess as well as
utilization of care and diabetes
self-management she's particularly
interested in community-based
interventions targeting low-income
african-american and latino men
dr hawkins recently received an nihr 21
grant focused on diabetes
self-management for african-american men
our second panelist is dr david cordova
uh dr cordova is an associate professor
of social work also here at the
university of michigan his research
focuses on latino health inequities
particularly as it relates to the
prevention of substance use and hiv in
adolescence
professor cordova
recently uh received an early career
development award from the center for
disease control and prevention to
develop and test the efficacy of a
family-based drug abuse and hiv in a
preventative intervention to be
delivered via the internet which we'll
be hearing about later he's very
interested in using community-based
participatory research
methods as well as qualitative and
longitudinal methodologies
to help us understand more about health
equities and equities in latino
populations
next is professor brad zebrak a
professor of social work here at the
school
his teaching and research interests are
in the area of health medicine and
quality of life he's particularly
interested in the effects of cancer on
the psychosocial growth and development
of adolescents with and young adults
his funded research also involves
evaluation of implementation and
psychosocial services and medical care
settings he's uh recently a new
principal investigator
on an nih r01 grant focus on genetic
mechanisms of health disparities
among adolescents and young adults with
cancer
our final presenter is dr anal zhang
he's an assistant professor at the
school of social work also here at the
university of michigan lots of good
intervention researchers happening uh
research happening here and he's a
clinical research director of the
adolescence and young adults oncology
program mr at michigan medicine
dr zhang is a health and mental health
intervention researcher with a primary
interest in psycho-oncology
and adolescent and young adult cancer
survivorship
dr zhang is a principal investigator of
a grant from julia's legacy of hope st
baldrick's supportive care research
program evaluating a tailored cognitive
behavior therapy for aya or adolescent
young adult cancer patients that you'll
be hearing about later today so that is
our panel
so i think we will begin
with dr jacqueline hawkins
hi everyone i'm just going to go ahead
and share my screen
all right
okay so
um my my name's jacqueline hawkins um
[Music]
thank you for inviting me today i'm
excited to talk with you all about my
work
especially as we celebrate the 100 year
anniversary of the um school of social
work
i'm an assistant professor in the school
of social work here at u of m i also am
a graduate of the joint phd program in
social work and sociology
i just wanted to mention as well i'm the
associate director of the curtis center
for health equity and training
and the co-director of the pilot and
feasibility program for the michigan
center
for diabetes translational research
and the title of my presentation today
is program active
african americans coming together to
increase vital exercise a combination
physical activity and cognitive
behavioral therapy program
but before i get started i just wanted
to do a land acknowledgement really
quickly
so in the spirit of healing and health i
acknowledge an honor that the university
of michigan resides on the traditional
territories of the three fires people
the ojibwe ottawa and bodawami
and that the great lakes region remains
home to multiple tribal nations
so our agenda for today
is i'm going to share some background
on the state of african american men and
diabetes and what we know about their
health behaviors
next i'm going to discuss my current
research including my research on
programming for black men with diabetes
and depression and then i'll just give
some concluding remarks and i look
forward to getting everyone's feedback
and answering any questions at the end
right
so my research area is comprised of
minority men's mental and physical
health diabetes self-management and
intervention development adaptation and
testing for this population
so the broader arc of my research right
now is fundamentally concerned with the
intersection of intervention research
for minority men and specifically
adapting existing interventions using
implement and implementation science
framework
so first i'm going to go very briefly
and give you all some background on
diabetes
it's relationship to mental health and
then i'll discuss briefly the state of
research on black men and diabetes
self-management
so nationally
in 2020 about
34.2 million or around 10.5 percent of
the population had diabetes and about 14
percent of men compared to around 11
to 12 percent of women had a diabetes
diagnosis and in comparison the rates
are slightly higher in michigan at about
11
and the disparities between men and
women are slightly lower and compared to
the us as a whole so in michigan
11.5 percent of men
have a diabetes diagnosis versus 10 of
women
so for people in the room who
may be unfamiliar with diabetes
diabetes is a condition in which the
body does not properly process food for
use of use as energy so most of the food
we eat is turned into glucose or sugar
for our bodies to use as energy and the
pancreas which is an organ that lies
near the stomach makes a hormone called
insulin to help to help glucose get into
the cells of our bodies so when you have
diabetes
your body either doesn't make enough
insulin which is type 1 diabetes or it
can't use its own insulin as well as it
should and that's type 2 diabetes
this causes sugars to build up in your
blood
so why am i
you know talking about type 2 diabetes
and type 1 and giving you this
background
it's to impress upon you that it's a
really serious chronic illness it's a
very tough health condition to manage it
can be
and it has really severe and serious
complications if it's not managed
appropriately
so engaging in several diabetes
self-management behaviors
is critical to living a healthy life
with diabetes
and again why is studying diabetes
self-management specifically so
important
if it goes unmanaged it can be
life-threatening so for example
complications from diabetes can lead to
health conditions such as diabetic
retinopathy which can impact vision
also because of the lack of blood flow
caused by diabetes unmanaged diabetes
can lead to nerve damage in the feet
amputation and also kidney issues
diabetes self-management means a daily
adherence to a rigorous routine that's
typically defined as checking your blood
sugar daily taking any medications
having a healthy diet regular exercise
and checking your feet for sores and
these are activities that individuals
with diabetes must engage in
every day or put themselves at risk for
the serious health conditions i just
mentioned
i'm going to take a moment
and do a poll
people with type 2 diabetes cannot eat
sweets
people with type 2 diabetes need to
watch their weight and maintain a
healthy balanced diet but in moderation
right so
as part of a healthy meal plan desserts
other sugary foods are definitely not
off limits
so
another motivation for my work and what
i'm going to be talking with you all
about today
is um
thinking about
diabetes and mental health so diabetes
is associated with a significantly
increased prevalence and risk for
clinical depression and depressive
symptoms
so people with
diagnosed with comorbid diabetes and
depression frequently exhibit some
sub-optimal health management a lower
quality of life and increased diabetes
related complications than persons with
one or the other diagnosed only
diagnosis only so even with successful
treatment as many as 80 percent of
patients with diabetes will experience a
depression relapse often leading to a
more pronounced expression of depression
prior studies have reported also that
african americans tend to under utilize
mental health services compared to
hispanic whites
so due to the strong association between
living with a chronic illness and
implications for mental health in recent
years the american diabetes association
has called on clinicians and researchers
to consider mental health when they're
working with people with diabetes
so
what this table is describing here is
that over the life course there are
psychosocial symptoms and diagnoses you
can expect to see in a person
with diabetes based on the research so
far and it also highlights the need for
both physical and psychosocial care
which means that people with diabetes
should not only be seen by physicians
and nurses but also should be
interacting regularly with mental health
care providers like social workers
who which are critical in helping people
with diabetes
in particular deal with the psychosocial
aspects of managing the disease which
are just as important as prescriptions
and testing and medicine and that's
where my work comes in
how can we utilize existing community
infrastructures and mental health care
providers like social workers
to help people with the diabetes live
healthier and happier lives
but before i get back into the except
for get into the exciting intervention
step i say
i want to take a step back and talk
about the current state of men's health
which is my population of interest
so what we know from the research is
that black men face a set of unique risk
factors that have a negative impact on
diabetes diagnosis rates and health
outcomes
including age cultural norms gender
norms socioeconomic status
and what we know from the research is
that black men are disproportionately
more likely to receive a type 2 diabetes
diagnosis at later stages of the disease
compared to black women and non-hispanic
white men
we also know that social context and
other factors influence the types of
masculinity that men construct and may
Be similar but also different in important ways for african-american men
15:25
be similar but also different in
important ways for african-american men
and we know from the research that this
construction can sometimes negatively
influence their diabetes self-management
and their interactions with care
and lastly we know that there's a lack
of research for both african-american
men
related to diabetes self-management
and
mental health care use
so i published several articles that
provide a foundation for studying
diabetes in african-american men and
i've looked closely at both psychosocial
and gender related factors
and how they impact diabetes
self-management in this population but
for the sake of time i won't go into
detail about these studies
the one that i will mention is a review
that i did a few years ago
with a couple of colleagues and we found
after looking at diabetes
self-management interventions from the
last 20 years
that black men who participated in that
research were on average only 15
of the sample
so
in our existing research
on african-americans related to diabetes
self-management
black men are underrepresented
so next i'm going to go over
next steps in my research uh with a
specific focus on my intervention
research that was heavily informed by my
previous work
um i also want to say you know i'm just
going to go
discuss this intervention really briefly
but i'm happy to talk more about it with
folks who are interested
so i'm presently the pi on two pilot
studies and the overarching goals of
both of the studies are to improve
health outcomes for black men with
diabetes
and my work focuses on the consistent
evidence
of failure to translate research
findings into clinical practice
i utilize the field of implementation
science whose goal is to study
determinants processes and outcomes of
implementation
of evidence-based interventions so i'm
present presently conducting two studies
the first is a peer leader diabetes
self-management support intervention
that's funded by nih
and the second which i'll be talking
with you about today is a physical
activity and cognitive behavioral
therapy intervention
and that is a pilot study
that was funded by the michigan center
for diabetes translational research and
the michigan department of health and
human services
all right
so um
i'm going to present on things a little
differently um well most folks tend to
present results i i'd like to talk with
you all today about a study in its
earlier stages
so in terms of specific aims the first
specific aim
involved
adapting an existing intervention
in collaboration with black men with
type 2 diabetes so we propose to adapt
an evidence-based cognitive behavioral
therapy and physical activity
intervention called program active
originally
um and at the active stands for adults
coming together to increase vital
exercise
and the second specific aim is to
conduct a pilot randomized controlled
trial
of this adapted intervention to evaluate
participant recruitment and retention
rates how satisfied men were with the
intervention
of course the impact of the intervention
on our primary outcomes which were
depressive symptoms and glycemic control
or
hba1c and also to assess the impact of
the intervention on our secondary
outcomes which are diabetes social
support and diabetes self-management
behaviors
so
my proposed
intervention is based on program active
like i mentioned and the goal of program
active originally was to assess the
comparative effectiveness of cognitive
behavioral therapy and exercise to usual
care on depression and a1c outcomes
that program was originally con
conducted in rural appalachia
and um also in an urban underserved
environment
all with folks with type 2 diabetes and
it involved 10 individual counseling
sessions and 12 weeks of community-based
exercise
so in terms of my ad adaptation we're
still going to have um all the
aspects i just mentioned however there's
going to be some important changes so
our intervention is going to focus
obviously on african-american men
um it's going to be based in detroit
and due to the documented impact of
gender norms thank you emma
of gender norms on diabetes
self-management and health behaviors in
general
we also included a gender norm scale
in the in our study questionnaires and
of course we're going to be
incorporating
ways to overcome the barriers that we
identify to physical activity and mental
health care use
in the pre-implementation phase
so i just wanted to say really quick you
know why
why cbt
combined with physical activity
specifically
in
the previous two inter
iterations of program active
depression remission among the
participants
um what in the in the intervention group
was five to six
times more likely and they sustained
gains uh or rather not gains but
improvement in their a1c
over 12 months so after the program
concluded
folks in the intervention group had
really great improvements in their blood
sugar
and when we checked or when
the pi the original pi checked in with
folks 12 months later
they had sustained
those improvements in their a1c
so we know it works but how can we get
black men with type 2 diabetes involved
in a program like this that's very
effective and beneficial
so
that's where program
active with an extra a comes in in my
work
what we're proposing to do is to give
all of the participants a nutrition
education program we're going to
randomize them to enhance usual care so
they're going to receive referrals to
community mental health providers and
pedometers if they're in the control
group
in the first phase we're going to do two
focus groups with black men with type 2
diabetes and the purpose of those focus
groups is to assess barriers and
facilitators to mental health care use
and exercise and also to get their
opinions on the feasibility and
acceptability of these intervention
materials
uh our second phase will be to randomize
to use the enhanced usual care
and then also to randomize bulks to the
combination cbt and exercise
intervention
and again that's 10 individual sessions
and
those are given in my study by licensed
clinical social workers and they get 12
weeks of community-based exercise and
those are six six of those classes are
led by personal trainers um originally
in the study also
we had partnerships with the northwest
activity center in the city of detroit
and the detroit community health
connection which
is a federally qualified health center
in detroit
[Music]
all right so the last thing i'll mention
the last couple of slides here
is uh while the intervention itself is
12 weeks we're conducting this study uh
with a three-month assessment period to
see if men were able to sustain any
gains they had during the program
our data is going to be collected at
three time points baseline three months
at the conclusion of the intervention
and lastly we're going to collect like i
mentioned three months
post-intervention
and this is below is just an example of
what the men need to do each week
for the intervention
these are some of the study measures
that we're going to be collecting
um obviously we're going to be
asking folks to come in we're going to
get their biometrics
um
during the course of the intervention we
ask them to keep a physical activity
diary everyone gets a pedometer
um and
we get everyone's like like i said
biometrics so
these are the last slides i promise
um so here's a poll
people with diabetes can fill when their
sugar levels are high or low
false
you may feel certain symptoms like
weakness or fatigue if your blood sugar
levels are low or high
but the only way to know your blood
sugar levels for sure is to test them
so people who don't test regularly may
have blood sugar levels that are high
enough to damage the body without them
even realizing it
so i just want to conclude with some
questions to consider
as we move forward with doing this
intervention
some things that have come up is you
know what's the best way to recruit and
retain
populations that typically do not
participate in research
and also have fewer interactions with
health care
and
the second question that we are
grappling with is
what other existing community
infrastructures might we utilize to help
sustain the program in the long term
and that's it i just want to thank
everyone for coming today and i look
forward to discussing
all right good afternoon everyone i'm
david cordova and i'm faculty in the
school of social work and i'm excited to
share with you a little bit today about
our program of research
that's focused on reducing substance use
and sexual risk behaviors and enhancing
hiv and sti testing among youth
so just to tell you a little bit about
the background of our program of
research and the significance
youth here on defined as adolescents and
emerging adults
14 to 21 years of age
are in a developmental period that can
be characterized among other things of
enhanced vulnerability
and particularly what we're interested
in here is the youth disproportionately
engaged in many risk behaviors that are
enhanced their vulnerability to
mortality and morbidity
so for example
national surveillance data from the
Monitoring the future study indicate that youth engage in many substance use behaviors.
27:36
monitoring the future study
indicate that youth
engage in many substance use behaviors
and so the most widely used listed and
illicit substance use
behaviors include alcohol use and
marijuana use
in addition
when we look at data from the centers
for disease control and prevention
many youth
also engage in condomless sex and last
sexual intercourse
given that substance use and condomless
sex
are risk behaviors for both stis and hiv
infection
it should not be surprising then that
youth are disproportionately impacted by
sti and hiv infection
in fact
despite accounting for nearly 25 percent
of the sexually active population
youth accounted for nearly 50 percent of
all new sti infections in the previous
year
in addition youth accounted for 25
of all new hiv
infections
despite the high prevalence of substance
use and sexual risk behaviors
and sti and hiv infection
sti and hiv testing a national
institutes of health research priority
remain relatively low among youth
in fact
only nine percent of youth report having
ever been tested for hiv in their
lifetime
in addition
many youth are not routinely screened
for asymptomatic stis as recommended
by the centers for disease control and
prevention
and yet relatively few interventions
have been developed to enhance the
uptake of hiv and sti testing
and prevent and reduce substance use and
sexual risk behaviors among youth
therefore the purpose of this study
was to examine the preliminary efficacy
of storytelling for empowerment
in enhancing the uptake of hiv and sti
testing across the trial
and reducing substance use and sexual
risk behaviors at three and six months
among you
so here we have our first poll question
which i believe emma will be
placing up
all right
so storytelling for empowerment is
theory driven
and informed by eco-developmental and
empowerment framework so from an
eco-developmental perspective
youth are embedded in interrelated and
interconnected contexts that both shape
the youth
and are shaped by the youth over time
and so our research and that of others
have demonstrated the utility of an
eco-developmental framework to inform
family-based interventions with a
particular focus on enhancing
parent and youth communication
in the present study however
We focus on the clinic microsystem
31:10
we focus on
the clinic microsystem
with the opportunity to focus on
clinician youth communication
in addition from an empowerment
perspective
youth have the necessary tools and
resources and strengths
and so here
we have an opportunity to link them with
important adult figures such as
clinicians to reinforce and to enhance
some of those strengths
so a little bit about the storytelling
for empowerment intervention so this is
an adaptation of a best practice that's
registered with the substance abuse and
mental health services administration
and has demonstrated in the face-to-face
version
effectiveness of preventing and reducing
substance use and sexual risk behaviors
among youth
and so applying the principles of
community-based participatory research
in conjunction with knight of prevention
principles
we adapted the storytelling for
empowerment intervention into a
web-based mobile health app
and so both youth and clinicians were
involved in the adaptation process
and informed all the decision-making
processes of the research
from the
submission of the proposal to the
dissemination of findings
and so here for example youth were
involved
in
developing the user interface and the
user experience of this mobile health
app so they through an iterative process
selected the colors selected the landing
page selected the content and the
process of this web-based app
and so s4e consists of an assessment a
risk assessment followed by modules that
focus on sexual risk behaviors substance
use
and hiv and sti testing
so with youth interact with this
web-based app
they first complete a risk assessment
that's focused on substance use sexual
risk and hiv and sti testing practices
following this assessment
youth then are provided with targeted
and tailored content
so for example if during the risk
assessment youth endorse
substance use behavior such as marijuana
use
and having engaged in condomless sex
then youth are recommended in initial
five videos and interactive content and
then in addition there's an additional
40 videos and interactive content
that were also youth identified and
developed that the youth can also engage
with throughout the duration of the app
and so as i mentioned the app consists
of uh
storytelling scenario videos and so here
we developed characters that resonate
with youth and place them in real world
settings and contexts that reflect some
of the situations
that uh youth discuss during the
formative research
beyond the inter the storytelling uh
videos youth also helped to develop
interactive content including for
example here
the the characters um in here they're
able to
touch on their mobile device different
parts of the body to see for example the
effects of
substances on various parts of the body
so beyond the youth facing act we also
developed a clinician-facing app that
communicates
synchronously with with the youth-facing
app and so here we interviewed
clinicians who informed us that their
clinic's risk assessment wasn't doing a
very good job of flagging the specific
risk behaviors
and also many were very lengthy and so
we streamlined this
risk assessment
and
more easily
flagged the specific risk behaviors for
the clinician and so what this did was
facilitate a clinician-initiated
risk reduction encounter where
clinicians can then focus in on the
specific risk behaviors that the youth
reported
which then allows them to provide
targeted
and tailored prevention services
in addition we also provided the
clinicians with the resource toolkit
again this is based on the use risk
responses where the clinician can then
not only reinforce specific prevention
messaging but also link the youth to
important prevention services
in the local community such as free hiv
and sti testing and substance use
prevention services
and so now that storytelling for
empowerment
has demonstrated high
feasibility acceptability
and preliminary efficacy
at 30 days post baseline
in the present study we hypothesized
that relative to the control condition
participants in the s4e condition
would
see an enhanced uptake of both hiv and
sti testing across the trial
in addition we hypothesized that
relative to the control condition
participants in the s4e condition would
report greater reductions in both
condomless sex and substance use
behaviors at three and six months post
baseline
although um
given the preliminary efficacy nature of
our study we didn't do any formal
mediation
analysis
we did test changes in our potential
mechanisms of change
namely youth clinician communication
as well as self-efficacy refusal skills
and given the preliminary
efficacy nature of our study
we de-emphasize the significance testing
and rather our purpose here was to
establish the necessary parameters to
inform a future randomized controlled
trial
okay so a little bit about the study
design
we recruited 100 participants in the
current trial
and to be eligible for this
study participants had to be between the
ages of 14 to 21
um
be sexually
sexually active defined as having had
oral vaginal or anal sex in the past six
months and that was because our primary
outcomes for hiv and sti testing
and then also report having access to a
mobile device as well as report not
having any tentative or firm plans to
move out of southeast michigan
and so participants were randomized and
then assessed at baseline
um and then reassessed at three and six
months post baseline and notably at six
months post baseline we had a 95
retention rate
so a little bit about our participants
we recruited a diverse sample of youth
44 reported as non-hispanic white 38 is
african-american 5 hispanic
with a mean age of approximately 19
years of age
25
were
less than 18 years of age and
approximately 66 percent identified as
female
so here's another poll question
okay
so with respect to hiv and sti testing
relative to control group participants
in the s4e group
reported a higher uptake of both hiv and
sti testing
across the trial and this produced a
small effect size
with respect to
past 90-day
condomless sex
participants
i'm sorry my
participants uh relative to the control
group participants in the s4e group
um reported greater reductions
in past 90-day cognitive sex at both
three and six months post-baseline
with respect to past 90 day marijuana
use
participants relative to participants in
the control group participants in the
s4e group reported greater reductions at
three and six months post baseline
and um
[Music]
both participants in the s4e and control
group
reported a 10
reduction at six months post baseline in
past 90 day alcohol use
and so then we examined the potential
mechanisms of change of our intervention
and both youth and clinicians in the s4e
group
reported a higher level of youth
clinician communication
relative to both youth and clinician
in the control group and this produced a
large effect size
additionally relative to youth in the
control group
youth in the s4e group reported
a larger increase
in self-efficacy refusal skills at six
months post baseline
and so our findings suggest that s4e
demonstrated preliminary efficacy
particularly in enhancing uh the uptake
of hiv and sti tests sti testing across
the trial
as well as reducing condomless sex and
marijuana use past 90 days
at three and six months post baseline
contrary to what we hypothesized
participants in both the s4e and control
groups
reported similar reductions in alcohol
use
so it may be that
perhaps
s4e doesn't have an effect on on alcohol
use
or
in line with nida prevention principles
we may need to enhance the content and
also incorporate some booster sessions
that focus on alcohol prevention
messaging
in addition
participants in the s4e group
also reported
higher increases in the potential
mechanisms of change namely clinician
youth communication and self-efficacy
and so this is an important advancement
in the scientific knowledge of mobile
health interventions especially given
that relatively few have identified
potential mechanisms of change
on substance use and sexual risk
outcomes
so finally show the promise of s4e
particularly in the areas of hiv and sti
testing
and on substance use outcomes
and
indicate that perhaps maybe a larger
efficacy trial may be warranted
the study findings however should be
interpreted in light of several
limitations
first
you know this is conducted at one youth
center community health clinic and is
not representative of
the entire clinic population nor the u.s
general youth population and so this
limits the generalizability
in addition
we relied on soft report measures and
although researchers
have shown the reliance of self-report
measures future research may want to
also incorporate some biomarkers in
future research
and finally
this study also recruited participants
who are currently seeking services at a
clinic and so we may be missing a very
vulnerable population and those youth
who are currently not in services and so
future research may work to to engage
and recruit participants who are
currently not seeking services
nonetheless
the present study
plays an important role in advancing the
scientific knowledge on mobile health
interventions
and the potential impact that they have
on preventing and reducing substance use
sexual risk behaviors and enhancing hiv
and sti testing among a vulnerable
population
thank you
all right i take it i'm good to go
people out there hello
you're good to go go ahead okay very
good thank you uh hi everybody good
afternoon good morning to you wherever
you may be
i'm brad zebrak professor here in the
school of social work
um and uh first just want to start by
expressing my gratitude for the
invitation to uh take part in this 100
year anniversary
of the school social work which has
played a big role in my education versus
a
doctoral student in the joint program in
social work and sociology
and now having been on faculty here at
the university of michigan for the past
13 years
i'm going to start you off with my poll
question
so emma you can go ahead and post that
up and i'll actually take a little take
a pause for a few seconds and
give folks a chance to
answer here
i'm talking about cancer i'm talking
about support
cancer support
for people affected by cancer so uh who
is it that provides psychological and
supportive care for cancer patients and
their families is it nurses is it
physicians is it social workers or is it
all of the above
there we go
most of you
did sort of catch that this was a little
bit of a trick question um it is true
um that all of these folks
do provide support
to cancer patients and their families
and i'm having a little trouble
advancing my slides here there we go
um
and yet even though that all these
providers do provide support
and care to some extent
i would argue that social workers are
the only professionals who are
specifically trained
um
uh and skilled to facilitate access to
the services and the resources that are
required uh to respond to the full range
of needs expressed by patients and
families affected by cancer
social workers the most knowledgeable in
terms of the evidence base
and they're most skilled to implement
the effective
and evidence-based interventions within
clinical care
and they're also oriented to issues of
equity and justice in their education
and and training so
in my presentation today i'm not
necessarily focusing on a specific
intervention i'm really making the
argument that social workers are
critical interventionists
in optimizing care for people affected
by cancer as well as for achieving
equity and addressing the disparities
which i'll talk about a little bit um
first a little bit of background on
cancer and really who was affected here
in the united states um
the lifetime incidence of cancer
for
adults in the united states is one in
two males and one in three females so in
essence uh one in one out of every two
males are expected to be diagnosed with
cancer at some point in their lifetime
and one in point one in three females
are expected
and you could see that if and when
diagnosed with cancer these are the the
three leading
types of cancer
that both males and females would would
or could be diagnosed with
as well as the leading cause of death
when cancer is the cause of death
you could see that pretty much both
males and females lung cancer
followed by prostate cancer for
men and breast cancer for
females and colorectal cancer are the
leading causes of the death so in
essence everybody in this country at
some point in their life will know
somebody with cancer
and for the last 60 years or so
malignant neoplasms which is cancer
along with heart disease have been the
two leading causes of death
for citizens in the united states
accounting for about 44 percent of all
deaths this is data from 2017.
these figures have
been a slightly decrease in in terms of
numbers of death absolute number of
death uh deaths over the last
few years but have pretty much rest
been steady um since 2017. what i do
want to point out given that we've all
now been through about a year and a half
worth of of
the covid
um
virus
um in one year ranging from 2020 to 2021
kovit has
with over 500 000 deaths uh can be um
identified as the third leading cause of
death in the united states over the last
year following cancer and and heart
disease now some people have tried to
argue
that given that people with chronic
conditions such as heart disease or
cancer are then most likely to be the
ones that
died
with their deaths attributable to covid
that perhaps those numbers for cancer
and and heart disease would actually be
lower you know again given if folks if
they've moved from cancer or heart
disease is the cause of their death to
covid um that
that those numbers would decrease but in
fact what we see and from data reported
by the cdc that actually the opposite is
true
that given covid we've actually seen an
increase in the excess deaths
attributable to cancer so in 2020
if you're looking at this this bar chart
here for both colorectal cancer and
breast cancer
colorectal cancer and breast cancer we
saw about 500 to 600 more deaths than we
would have
had covid not occurred in this country
and what we're seeing projected over the
next 10 years are actually increases
in the projected rates of death
attributable to colorectal cancer or
breast cancer because of covid and the
explanations that have been provided is
that covid has led to a lot of other
pressures within our health care system
which is which has attribute contributed
to delays in diagnosis we know that
early detection and prevention is one of
the key ways of preventing morbidity and
mortality due to cancer but because of
covid we've seen many delays in
diagnosis
we've also seen interruptions or
alterations and treatment regimen folks
showing up to the hospital or not even
going to the clinic for their
chemotherapy or their radiation because
those spaces within hospitals have been
taken up by people who have coveted
and need that that kind of attention
the loss of employment as well as the
associated loss of health insurance has
minimized has led to a decrease in
access to care again without that that
key without that health insurance key to
get in to see a doctor um that's going
to contribute to delays um and further
contribute to these risks of morbidity
and mortality due to cancer
we've also seen decreases in practices
of preventive care we've seen increases
in small
of this excess rate of death
attributable to cancer and influenced by
covet 19.
um
the federal government and she
conceptualized cancer as not just a
disease process with associated medical
treatment but also a succession of
social
interactions and psychological
conditions that accompany uh including
um
uh holland and roland who have uh date
back to some of the original founders of
this notion of integrating the
psychological and social aspects of
of life into cancer care
they've identified these five different
domains in which people our lives are
disrupted or affected
um
uh when when impacted by cancer
sometimes referred to as the five d's
this first in terms of distance cancer
impacts on on uh distance between in
relationships altering interpersonal
relationships um there's disfigurement
the experience of body image or sexual
image and integrity of the physical body
people feel that um
in their effects of cancer in their body
it's disabling uh including a disabling
of of people who in their life their
life goals and and dreams that they have
for their future uh regardless of
however old they might be um they
experience those disruptions when cancer
strikes um they're oftentimes forced
into dependence on others
you know living wanting perhaps desiring
to live independent lives and yet
oftentimes then having to require
help from others being positioned to
have to ask for help from others
can be a very challenging and
uncomfortable position for folks and
then of course confronting one's own
mortality uh when diagnosed with cancer
so the the psychological and emotional
fallout
that occurs alongside the biology and
the treatment for cancer are really key
and critical to attend to and i would
argue that this is really the domain for
for social work and cancer care
there have also been conceptualization
uh conceptualizations of cancer as being
experienced as psychological trauma um
here you can see some some theoretical
uh presentations particularly by george
bonanno uh well known in the field of
psychology and trauma
where he's theorized that when when
folks are exposed to trauma
they might follow one of four different
trajectories over a period of time that
for some people and if you look at that
line there at the top of this this bar
chart i'm sorry top of this graph line
graph you'll see that um for some people
at the at their experience of trauma
their psychological response their their
their psychological social functioning
is severely impacted and that over time
um that impact uh remains severe over
time and he has labeled that a chronic a
chronic trajectory of trauma
the second line which begins that dash
line and then and then decreases over
time that some people at that exposure
to trauma experience perhaps moderate
levels of distress at the time of
exposure but then recover over time
assumedly because they have access to
either intrapersonal interpersonal
community-based resources uh that play a
key role in in their emotional or
psychological recovery over time
uh for others who may experience a
moderate moderate level of distress at
the time of exposure um that that level
may actually increase over time and is
labeled a delayed trajectory and there
may be again other environmental social
factors
that come into play
that increase the likelihood that these
folks will actually increase in their
levels of distress over time after being
exposed to that trauma and then finally
is a subset of group of folks following
what's called a resilience trajectory
that they have they they presumably have
intrapersonal and and environmental
resources available to them at the time
of their exposure to trauma which may
minimize that
uh their emotional response to that
trauma and and and remains um within
somewhat of a mild
trajectory over time
so i was interested in testing whether
or not this this model actually applied
to teenagers and young adults
impacted by cancer
a population that i've been interested
in uh both as a clinician working in the
Field of pediatric oncology
59:06
field of pediatric oncology uh as a
social worker and then making this the
focus of my uh academic research and in
fact in our in our uh a longitudinal
study of 152 adolescent young adult
cancer patients uh we did find over time
that um
the that subgroups did follow these
different trajectories so you can see
here uh that in terms of a chronic
trajectory uh 11.8 percent almost 12
percent of our sample remained um uh at
a significant uh clinically significant
levels of distress over time another 15
of them followed that delayed trajectory
uh about just under 20
followed that recovery trajectory and
about half
um followed a resilience trajectory and
then to the right in the other column
you can see there was a comparable study
published in the literature that did a
similar work with adult patients
diagnosed with colorectal cancer and
again found a subset of folks following
in both the chronic the delayed the
recover and the resilience
trajectories
and i think this that this work is um
is meaningful and significant
particularly today in an era where you
hear discussions around what's called
precision medicine
the ability to identify
uh or detect um or predict which which
folks are going to be most significantly
impacted in in negative ways by their
condition uh so that we can really focus
our resources
on those folks who are at the highest
risk and then
titrate or or moderate or modify uh the
attention given to others
based on the times
time points at which they might express
express a need
within the cancer field regardless of
type of cancer diagnosed regardless of
the age of the the sample and the study
we've seen consistent findings of
anywhere from 30 to 40 percent of people
diagnosed with cancer uh demonstrate
symptoms of psychological distress
which could be attributable to
symptoms of depression or anxiety they
may be a function of of um
of tension in in relationships intimate
relationships uh there may be other
challenges in in the home in the family
uh that are that are contributing to
their distress and and may subsequently
serve uh as impediments or barriers to
accessing or receiving um
optimal care
so in terms of the role that psych uh
that social workers play within the the
the domain of cancer care
um the institute of medicine has defined
psychosocial services as the
psychological and social services or
interventions that enable patients their
families and health care providers to
optimize biomedical care and manage the
psychological behavior social aspects of
illness and its consequences the point
here is that managing the psychological
and social impact is is equally as
important to the provision of the the
biomedical care because without
attending to the barriers of care what
good is the chemotherapy what good is
the the medical intervention if folks
can't get there if folks can't optimize
their um their access utilization and
benefit of that treatment
and if we look at at psychosocial the
research in this field um since the
1970s the first those are the first
empirical studies of psychological and
social impact of cancer identifying
these domains and what social workers
practice
um but then by around 2008 a landmark
study by the institute of medicine came
out uh looking at the extent to which
psychological and supportive care was
being made available
uh to patients and families in the
extent that they were benefiting from
that and they reported that most folks
in need were also the least likely to
get those needs met
and then some work in 2016 looking at
the organizational structures uh the
resources across cancer centers in the
united states there was an uneven and
unequal capacity
some centers across the country were
very highly resourced uh had had very
well established ratios of social
workers to patients uh whereas on the
other end uh there were some uh centers
that were really doing you know poorly
in terms of having resources including
social workers available uh for their
patient population
um i want to finish up in the last few
minutes by introducing an emerging
scientific area one that i've been
pretty interested and excited about uh
that also aligns with
contemporary attention to social
determinants of health and looking at
the upstream factors that contribute to
downstream needs and particularly in the
field of cancer i've always been
intrigued by sarah gillard's work
in which she has posed this question
about trying to get an understanding of
how the the environment gets under
people's skin to literally affect their
health outcomes and then disparities in
those outcomes um and if we look at the
way that cancer treatments have evolved
over the years we can kind of see and
recognize the ecological context that
has driven not only the biomedical
approach to cancer treatment but also
the psychosocial care i think most folks
are unders understand
the notion that chemotherapy literally
chemicals that are injected into
people's bodies as a way to attack
cancer cells
cancer cells are are mutating genes
they're they're they're genes that are
replicating out of control and the
purpose of the chemotherapy is in
essence to stop that um that
reproduction of those of those um
uh mutating genes um but we've we've
made advances uh primarily due to the
advances in in genetics and genomics
where we're now understanding that those
cancer cells exist within it sort of if
we're thinking ecologically here the
microbiome those cancer cells are living
in a neighborhood of other cells and
some of those other cells feed those
mutating cells feed those cancer cells
so the next level of of treatment
evolved to to start thinking about well
maybe if we if we also can target the
neighborhood of those cancer cells
perhaps starve off the the energy to
those cancer cells that could become
another viable way of treatment and
we've seen that evolution in in cancer
treatment over the years attacking or
addressing the microbiome
but that microbiome
exists within a next level of concentric
circle or context which is the immune
system and today we've seen emerging
therapies particularly gleevac for those
folks diagnosed with uh particular
levels of types of leukemia and lymphoma
as well as the emergence of
immunotherapies car t
being one of the more
recent
inventions here that that target the
immune system uh recognizing that the
immune system operating uh uh can affect
both that microbiome that neighborhood
of the cancer cells as well as the
cancer cells themselves and that the
immune system can be observed in terms
of a genetic profile
and this whole basis now for precision
medicine really has to do with
identifying biomarkers being able to to
look at a gene profile
and and and look at its association with
the function of the immune system
and then be able to assign a particular
immunotherapy
that will be responsive to
the genes that are being activated um in
this particular case so when we hear
about searches for biomarkers this is
what our biomedical scientists are
trying to do they're trying to look at a
at a gene profile
and use it as a way to predict which
patients are more or less likely to
respond to a particular
um a particular therapy
well again moving on thinking
conceptually
those those biomarkers our genes are
responsive to the brain the brain is the
conductor of gene activation it's the
conductor of our our entire bodily
function and we know that the that the
brain is susceptible to stresses uh to
hormonal stimulation
and these are the things that come from
our social environment thus we're making
the connection and here we get an
example tamoxifen therapy
for women diagnosed and treated for
breast cancer are often put on tamoxifen
afterwards as a way to
sustain or maintain brain function cns
function in order to
influence gene function which then leads
to
controls of physiology of bodily
systems and bodily functions so what i'm
doing here is saying that if all of this
is then being driven by the brain and we
know the brain
confident to engage in their own care
even their their their psychological set
their intention to uh attribute meaning
or have a sense of purpose in life uh
related to cancer
um
this is the domain of social work and
this is where we can play a key role
um in in responding and um
and uh complementing uh treatments for
cancer
um
this is um
where things are at today this is i just
probably tried to cram in a whole
semester's worth of of biology in a
short 20
it looks like brad might be having some
trouble with the uh camera but i think
he was just about to end up so i think
what we'll do is move on to and now
uh looks like we have a poll question
we'll move on to dr zhang and then
there'll be a chance later for dr zebrak
to uh answer some questions thanks a ton
brad
really great
i hope everyone can see my screen
yes
if you cannot okay cool
all right let me restart my timer
okay um good day everyone it is really a
pleasure having the chance to share with
you some of the work that i have been
glad in collaboration with my colleagues
from um school of social work michigan
medicine in supporting the complex
psychosocial needs among adolescent and
young adult aya's diagnosed with cancer
my name is danielle john i am an
assistant professor at the um school of
social work
it's always nice to do a cancer related
presentation following brad zirak just
because he lays such a nice ground and
foundation
for the important context of
psychosocial care for cancer survivors
and
in this case i wanted to argue that for
aya
aya is an age defined population with
cancer between the age of 15 to 39 years
old which include three distinct
developmental stages which are mid to
late adolescence those 15 to 18 years
old emerge in adulthood 18 to 25 years
old and the young adulthood which is 26
to 39 years old
and throughout their cancer journey ayas
with cancer are continuously confronted
with multiple stressors including
invasive curative treatment options that
are often painful and burdensome for
them the immediate treatment symptoms
and side effects such as nausea insomnia
and significant changes in one's
appearance
also there's a long-term and often
irreversible impact on ai's fertility
capacity lung or heart health health etc
and of course there are many unique
psychosocial challenges that are
specifically belonging to the aoi
population which includes uncle
fertility financial toxicity sexual
health just to name a few and many of
these have long term and lifelong
implications for the wellness of aoi is
diagnosed with cancer
so when combined all these factors put
aya with cancer at significantly higher
risk of experiencing psychological
distress especially depression and
anxiety so before we start the first poi
i want to provide you the context and
then we'll do the poll
so according to the national institute
of mental health and data from the 2019
nas nhd uh data set there is an
estimated
7.8
of the u.s adults the general adult
population 7.8 of them experience
depression so the poor question here is
what is the estimated rate of depression
among adolescents and young adults with
cancer brad kind of has already allured
to that idea a little bit we know it's
definitely higher than the general
population
but i would just give everyone maybe 10
seconds trying to
you know putting your thoughts with
regard to the
prevalence rate of depression among aye
is diagnosed with cancer
all right you can keep voting but i'm
going to give you out the answer
the answer is 25
so while there exists no rigorous data
to systematically evaluate the rate of
depression among aye is diagnosed with
cancer existing studies estimated the
prevalence rate of depression among ays
with cancer ranged between 16 to 42
with the recent meta-analyses estimating
an overall prevalence rate of 25
aya survivors having depressive symptoms
um we have a next pool um and uh
we can pull out the point and i'm going
to read out the question right so for me
as a clinical social worker my immediate
i i would immediately start to wonder
now so we know that depressive symptom
is highly prevalent among ayas but when
do we have evidence-based interventions
for us to support this population and
the question here is when compared with
interventions for pediatric cancer
survivors psychosocial interventions for
psychological outcomes among aye
survivors are
equally effective
more effective than the pediatric cancer
survivors less effective than or the
evidence remain inconclusive
[Music]
so
our team recently published the meta
analysis in the journal critical reviews
in concology hematology we looked across
61 clinical trials of supportive
interventions for pediatric
and ay cancer survivors and one of the
key findings unfortunately for me as an
aoi cancer researcher was that on
average psychosocial and supported
treatments effect was significantly
lower among aya cancer survivors than
their pediatric counterparts were
diagnosed with cancer
this means that although we know that
efficacious depressive treatments are
available for ayac in general meaning
most of those without cancer such as
cognitive behavior therapy when it comes
to deliver research-supported treatments
like cbt to ay cancer survivors these
interventions are not as effective as
they stand now
and published studies have found that
cbt is only effective for ay cancer
survivors when
first the treatment option is available
and easily accessible
to the population and more importantly
when aya cancer survivors are compliant
engaged and cooperative with available
treatment options
both sets of requirements however have
not been successfully or at least to my
knowledge actualized in the real world
practices of psychosocial oncology
supporting ays with depression
first um i think it doesn't come as a
surprise that cbt is often not easily
available or accessible to ais with
cancer mimicking the pattern of mental
health professional workforce shortage
nationally and internationally studies
have consistently reported additional
factors that contribute to the mental
health workforce shortage in
psychosocial oncology supporting ayas
one factor being the required expertise
to address mental health conditions
co-morbid with cancer
and even for those nci designated
comprehensive cancer centers such as
michigan medicine that have certain
level of mental health resources and
workforce available a waitlist is often
long between usually between one to
three months and not all providers are
fully trained in delivering
evidence-based therapeutic intervention
such as cognitive behavior therapy and
with recent advances in computer and
mobile technologies tech-assisted cbt's
tcbts have been found as a promising
solution to reduce the access barriers
facing many aya cancer survivors in need
of mental health support
with that said however although tech
assisted cbt's tcpts are highly
promising in addressing access areas
most programs
are academically oriented and text heavy
and does not engage clients effectively
in addition to our knowledge there
exists no tcpt
that specifically is designed to meet
the unique medical and psychosocial
challenges confronting aoi is diagnosed
with cancer leaving a major gap in the
aoi psycho-oncology literature
so taken all together our team
identified four key areas of improvement
that are needed to address depression
among ays diagnosed with cancer
first it is important to integrate
cancer-specific disease management and
educational content into tcbt treatment
to ensure content relevance
second it is critical to be innovative
to create fun and engaging treatment
content that are attractive to aya
cancer survivors a younger population
that is known to be difficult to engage
in the therapeutic process
third it is also important to
accommodate visual materials that are
aesthetically appealing and
developmentally attractive to aya
populations including as specific
especially for those who are
traditionally underserved like racial
and ethnic minority aya cancer survivors
and finally it is critical to consider
platform-based based tailoring features
that are easy
flexible and allow low-cost
tailoring to maximize individualized
treatment options and maximize treatment
uptake
the program that i'm sharing with you
all today is highly pro is a highly
promising platform that simultaneously
meets many of if not all of the areas
that were mentioned the previous slide
the program is called mind your total
health the myth program
which was named by a group of young
adult cancer survivors who
overwhelmingly expressed their
preferences of not having the word
cancer in the naming of the program and
also found somewhat the acronym myth
being cool
the myth program is an aya cancer
specific tcpt program that is tailored
based on its parent program
entertainment well which was
co-developed by doctors addie weaver and
joe hemley with support from the
national institute of mental health and
for those of you who attended the first
lecture series dr weber shared her work
delivering the ross program to rural
residents with depression and there's a
sister program with the myth program
inheriting many strengths of the parent
program the myth program engages its
user with a retrospective engaging
storyline and include most sessions
ending with a cliffhanger to boost
treatment compliance
in addition myth utilizes platform-based
tailoring features from entertainment ul
and thoroughly modify those educational
and motivational panels for
developmental medical and the
psychosocial needs of ay cancer
survivors which i will further elaborate
just in a minute
but first and foremost myth contains
core therapeutic components of cbt
interventions including cognitive
restructuring behavior activation and
problem solving
although platform-based tailoring
features are available in the myth
platform those contents related to core
cbt fatality including the order of
delivering certain content are locked in
a sense
and cannot be easily changed to ensure
program and treatment fidelity
when we are tailoring the program we
engage in a community and stakeholder
engaged process we interviewed aya
cancer survivors themselves
uh
leaders asking for their imp
the
static and potential helpfulness of the
client of the content
so here are just some of the screenshots
of the storyline throughout the sessions
as billy the main character the blue the
blue balloon uh retrospectively
walking the user through their
experiences of overcoming depression as
briefly mentioned earlier a notable
innovation of the program includes a
cliffhanger effect and just to give you
an example in session six the story line
ended with billy the balloon debating
whether she should take up in an offer
to meet with her just reunited high
school sweetheart johnny at the diner
but still haven't heard back from the
text that she sent johnny earlier and
that's the end scene of that session
naturally uh the users would need to
come back to session seven to figure out
what happened to billy did billy go did
billy not go so that's what we were
thinking about the cliffhanger
and that is an effect that occurs in
most of the sessions
in addition we also made major tailoring
of visual materials motivational quotes
and cbt related examples throughout the
sessions to better reflect the program's
relevance to a population that has
cancer and are younger and as you can
see we were also mindful in ensuring
those materials that are inclusive of
different identities to the best of our
abilities
most importantly we were very
intentional in integrating
cancer-related content into the tcbt
component
such as behavior activation just give
you an example the screenshot on the
lower left side is a tailored
educational panel doing brainstorm
sessions with aya survivors on potential
Activities for pleasurable and for achievement
01:23:38
activities for pleasurable and for
achievement activities
um
as you can see we included some low
intensity physical activities taking
into account the likely physical
limitations and some of them are timely
some of our more long-term during and
after one's cancer treatment and we also
suggested cancer management as part of
the activities for achievement to
encourage users aoi survivors better
health management behaviors
finally i just wanted to underscore kind
of the full potential of the platform
and it can be easily achieved for us to
create more individualized platform
materials
such as an educational panel
specifically designed for ayes serving
in the military with the diagnosis of
lymphoma on the lower right side of the
slide and our team have recently
submitted an ron application to the
department of defense proposing a
military-specific aya program
we were beyond grateful to receive the
psychosocial grant from julius lexi of
hope uh
hero fund through the baltics foundation
to conduct a pilot randomized control
trial to evaluate the feasibility and
preliminary efficacy of the myth program
in reducing ay cancer survivor's
depressive symptoms using primarily a
clinic-based recruitment strategy at
michigan medicine in conjunction with um
community-based participant
self-referral we recruited participants
between the age of 15 to 26 years old
with a current cancer diagnosis and
experienced moderate or greater
depression
a participant can either
receive active curative treatment or
within five years of post-treatment
survivorship and the exclusion criteria
include if participants as receiving end
of life care or current currently
experiencing acute mental health
conditions such as
active psychosis or at an elevated level
of self-harm
over over a eight month period between
september 2020 to april 2021 our team
con contacted 49 potentially eligible
participants 20 of these participants
were not interested in the study for
various reasons such as identified not
depressed uh or not interested in a
computer-based program due to
overexposure to computer
and uh in addition 12 potential
participants did not meet the study
inclusion criteria including nine with a
a low level of depression two
participants were receiving end of life
care and one participant reported
history of suicide attempts over the
past two months
consequently this study has resulted in
17 participants being randomized into
the treatment alarm and the control arm
so participants in the treatment arm
received the myth program which is an
individual based a session tcbt
delivered on a weekly basis the
participants were instructed to complete
the program weekly but they have up to
10 weeks to complete all eight sessions
upon completion of each session a
master's level trained research
assistant would follow up with a five to
ten minute checking phone call to
reinforce session content and link
specific session content with
participants cancer management all
research assistants were instructed not
to provide additional therapy we decided
to add this clinician follow-up based on
the best practice guideline of the
literature but the brevity of the
clinical contact here is important
because five to 10 minutes of the
of the interpersonal follow-up does not
really
further
strengthen the mental health workforce
given the gravity of the content
similarly participants in the control
arm received an existing tcpt program
beating the blues which is as you can
see had very similar intensity in their
frequency as the myth program uh the
other protocols were all identical with
the treatment arm the only difference is
that the beating blue is a rather
academic and a text-heavy generic
version for depression and it does not
have cancer-specific tailoring for the
for the participants so we evaluated
the feasibility acceptability and
participants clinical improvements using
well-established and psychometrically
validated scales
given the constraint of time i just
wanted to highlight some of the key
findings here first eighty percent of
the participants in experimental arm
achieved the feasibility and point
evidence by completing six out of eight
mid sessions versus in the control the
feasibility
endpoint was reached by 71.4 percent of
the participant
there are two more nuanced pieces that i
would like to share
uh six out of the eight participants in
experimental arm who achieved the
feasibility endpoint completed all eight
sessions whereas only two participants
in a control arm completed all age
sessions and one participants in the
control condition reported the
intervention not being helpful as a
reason for drop out whereas now no
participants cited this reason for the
myth program
in terms of the treatment and efficacy
participants in both groups reported a
statistically significant reduction in
depressive symptoms measured by the
phq-9 scale but it's worth noting that
the between group effect size was large
in its magnitude meaning participants
receiving the myth intervention reported
significantly and clinically greater
reduction in depressive symptoms than
their counterparts in a control arm
additionally it was encouraging for us
to observe that participants in the
experimental arm reported a
statistically significant reduction in
anxiety as measured by g87 but not in
the control condition
some key strengths that we learned from
the participants about the platform
the first is that participants really
liked the cliffhanger effect and they
found it very effective to engage them
to come back to the sessions several
participants also considered the program
as a valuable mental health treatment
option that can be embedded or
integrated into their cancer care
especially for those who are doing
outpatient chemo or infusion where they
probably don't have other things to do
and they think this can be a good way to
keep them distracted but also to learn
something about cbt and their depression
all participants appreciated the privacy
and the safety of receiving cbt remotely
and many participants praised the taylor
content being medically relevant and
their experiences are uh
and uh and the they founded the platform
aesthetically attractive to them a
couple of key
kind of learning lessons learned uh
unanimously participants wish that billy
and herself is a cancer survivor because
currently we really we need to develop
an entirely new storyline to make that
feasible and our team are really working
hard to to
obtain external funding to make that
possible
they also recommended uh having
integrative homeworks to having homework
centers to have a cell phone based
application to facilitate cv to
facilitate cbt homeworks that allow a
linkage with their mobile notifications
or calendars and a system integration
with their current cancer care between
the program and their current uh current
medical facility
um i wanted to acknowledge my
collaborators from um school of social
work and michigan medicine and again uh
the generous uh support from julius
legacy of hope uh herobot from
symboltrix for stephanie this study and
i would like to end with this quote
which was actually a julia's favorite
quote which says you never know how
strong you are until being strong is the
only choice you have one of the greatest
privilege of the job that i have and the
research i do is witnessing the never
lasting strengths uh resilience and
everlasting strengths and resilience and
hope from those who are battling with
cancer at a younger age they have been a
constant source from my own strengths
and motivation and i thank them very
much for that and i thank you for
listening
terrific thank you so much now and uh
sorry i had to sorry i cut brad off with
the technical stuff he will be uh
present of course for the question and
answers
i need to turn now uh a great
opportunity to sum up these talks and
give some messages of her own dr jamie
mitchell as our discussion thank you
jamie
hello everyone
um what a wonderful set of panelists and
presentations
so i just have a few concluding remarks
all of the innovative programs of
research that we just heard about today
are reaching populations that are
understudied underserved and or
disproportionately overburdened by
chronic conditions and health needs
such as diabetes in black men with dr
hawkins enhancing hiv and sti testing
among youth with dr cordova
mental health among adolescent and young
adult cancer survivors with dr zhang and
psychosocial and supportive cancer care
with dr zebrak
each of these presentations demonstrates
the future of social work research
specifically how as our social work
grand challenges state we can leverage
the power of technology for social good
for example dr
cordova is at the forefront of using
developmentally and culturally tailored
technology-based preventive
interventions in this case a mobile app
to reach youth clearly dr cordova
understands how this intervention can
help clinicians flag risky behaviors and
then how this technology can also
provide direct feedback to clinicians to
improve the interventions they deliver
and the linkages that clinicians can
provide to services in the local
community
further dr zhang is advancing the
science of reaching adolescent and young
adult survivors of cancer who are
experiencing depression and he's
reaching this population with fun
engaging developmentally appropriate and
well-tailored interventions
as with all of our incredible social
work sciences he's using a person and
environment approach that integrates
specific knowledge of the cancer
experience into the intervention to make
it more meaningful and efficacious for
those that it's designed to serve
we also saw a common theme of cognitive
behavioral therapy as an intervention
across multiple presentations today
this signals to me that our social work
researchers such as dr jackie hawkins
are ensuring the interventions designed
to tackle persistent health disparities
particularly in communities of color
are using holistic approaches that bring
together the best available science in
addressing physical health and mental
health concurrently
it's so incredibly gratifying to see
examples of rigorous scientific
interventions that are actually designed
for real people with real problems and
not only abstract interventions designed
for only ideal laboratory convention
conditions
for example dr zebrak illuminated how
cancer is experienced as trauma
impacting the psychological functioning
of individuals and families and
producing harmful chronic stress over
time
his work gives us a hopeful glimpse into
the future of social work research where
social work scientists are working
actively alongside basic and medical
scientists to apply precision precision
medicine to predict or identify
individuals who may most benefit from
certain targeted therapies to improve
both cancer outcomes and psychosocial
and supportive cancer care
dr zebrak's research on the emerging
area of social genomics or how social
conditions in the environment literally
get under the skin to affect health
outcomes and disparities nicely ties
together an underlying thread among all
of the panelists
each of these panelists are addressing
social conditions in physical and mental
health and the integration of both that
are powerful factors such as stress
sexual health exercise mental health
that shape opportunities for health and
longevity particularly amongst
vulnerable or underrepresented
populations
these are also factors that shape
longevity and well-being across the
lifespan
we are so fortunate to have such a
wealth of scholars doing this work
in this school of social work at this
time
the research collaboration and
innovation that our panelists displayed
and that really is indicative of our
entire faculty and staff in the school
of social work is an excellent
representation not only of the previous
100 years of work that we have achieved
but also it's a peek into the future of
where social work science is headed for
the next 100 years to come thank you
all right we're going to be moving in to
our q a portion now so jamie you should
see some questions
um in the chat or in the q a
let's go ahead and prioritize those and
then when you've run out i can send you
the ones that came through from the chat
okay wonderful can you get us started
just so i'm not uh clicking around you
bet
all right so our first question is
actually for brad um did you also look
at parents of youth and their trauma
reactions
i have not in in my own work um although
it would certainly make sense to
to acknowledge people within the context
of their families
uh there is a pretty sizable body of
research um around the experience of
caregivers of loved ones
uh
of folks who are experiencing not just
cancer but other other chronic
conditions
um you know just to to give you a brief
you know picture of what this what this
often looks like um you know our current
system of care um excuses folks from a
health care system very quickly you have
cancer patients who are going home
with ports
and they're told to keep those those
ports those catheters cleans for the for
their repeat of visits to the to the
cancer center for their chemotherapy
and and and oftentimes it's the the
spouse the partner the significant other
the cancer patient who receives either
an implicit or explicit message about
how you have to keep this catheter clean
so that your your loved one doesn't get
an infection
um and have to come back to the hospital
i mean just imagine how stressful and
scary that must be
for a family member to be to be told
that so i think the question is on
target personally my own work hasn't
hasn't focused on that that question but
there are folks out there doing that
work
thank you so much brad
um there's another question here in the
q a regarding the cancer presentation
and i think this actually could go to
both dr zebra and dr zhang um with the
prevalence of cancer skyrocketing and
even more so in the years to come
this
attendee is wondering why insurance
companies may make it more difficult to
get certain screenings for specific
cancers to jump through hoops or meet
certain age requirements
even if the age of onset for some of
these cancers may be decreasing do
either of you have any insight into that
cancer is cancer treatment is business
and the finances of cancer care and
health care in general
just like any other business any other
corporation are looking to
minimize financial risk and maximize
profit
very succinct there's actually a related
question
and that is directed toward dr zhang and
that is in addition to the shortage of
mental health providers does lack of or
type of insurance potentially impact
access to cbt treatment and how so
it does and i think that's such a
great and an important question
just a story to share
while we're doing this study we're doing
uh cbt for aoi cancers we've been
approached by
younger
parents of younger
cancer patients and survivors and older
and they'll reach out to us to the study
just because that at that time they
didn't have insurance to cover
uh their mental health services and they
were
unfortunately desperate at a time and
just want to find anything that can be
supported to them um so i think that's
just an attestment to this great
question that insurance status does
uh significantly impact the access
um
and if i may just quickly add i i think
it also speaks to the importance of
having social work researchers doing
interventional research because uh i
think
it's fair to to say on behalf of all my
colleagues that we also think from a
social justice lens and health equity
lens when we're thinking about treatment
access as we're developing this so i
think you know as we further grow into
the field as a profession in terms of
the technology assisted intervention we
may be able to move the needle a little
bit
wonderful
there's another question about whether
uh essentially what is the literature
base or well you know are there any
studies on the benefits of support
groups for any of these populations and
so i think we're hearing a lot about
technology assisted interventions but
support group still seems to be a tried
and true potential intervention would
anyone like to speak to that
in any of the populations that we heard
about today
in in terms of of cancer support groups
i think the um uh you know the empirical
studies have shown that support groups
have a um a moderate effect um
but i think in you know what you're what
you're seeing in those studies is is an
average
uh that for some people support groups
are critical to their mental health and
their their survival and their
adaptability while dealing with cancer
uh there are other folks who
they're you know they're attending
really doesn't have any uh measurable
effect at all so you get the average um
which comes back to the point that i was
trying to make around precision medicine
you know there are a lot of
therapeutic
psychosocial modalities out there and i
think our challenge ahead is to get
folks matched up with the treatment
modality that is most likely to benefit
them in a personal way
wonderful and dr hawkins i know that
you're it's not the study you presented
today but you have done uh quite a bit
of work on peer interventions um and so
not traditionally support group but
certainly um interventions that utilize
peers um can you illuminate any of the
the work that you've done or research
that you know about in that area
um yeah so actually we do call them
support groups
but they're they are very specific to
diabetes self-management so they're
diabetes self-management support groups
and the other
work that i do i was part of a project
called praise that was done in 21
churches in flint um
toledo and detroit
and
we trained peer leaders so folks from
the community to run the support groups
and the way that they run them is
you know whatever issues come up so it's
not a scripted or lecture style it's
more of a dialogue and the great thing
um that happened from those
support groups with the peer leaders is
that
people were able to learn from each
other it really normalized
the stigma that can sometimes come up
around having diabetes and the different
issues
that folks face
support groups are a really powerful
tool and i'll say for the work that i do
we are um
focused on doing those types of support
groups and training through leaders
specifically for men
and i found that there are some issues i
apologize mcdonald's
there are some issues that are specific
to men um that that come up
um specifically uh in these groups that
didn't come up in
The groups with men and women fantastic
01:44:31
the groups with men and women fantastic
and dr cordova i want to pull you into
the chat as well have you done work or
are you aware of work that utilizes the
power of peer support and some of the
work that you're doing in sexual health
with um with youth
yeah so actually it's interesting we uh
we actually had some pilot funding
to have uh peers deliver the
intervention
as opposed to clinicians
and so we had put that during the covet
we put that on pause
but we're now starting to resume that
and so
we're now laying the foundation for that
as a way to see if um
if there's any preliminary efficacy
feasibility acceptability with having
peers deliver the intervention
wonderful it sounds like there's a lot
of literature and a lot of research even
being done within these projects in the
peer space i want to return to you dr
zhang there's several questions in the
chat about the next directions for your
research as well as uh whether some of
the inclusion and exclusion criteria um
there was one question about whether uh
in your work uh did it include or
exclude patients that were initially
diagnosed as pediatric patients and then
relatedly are you at all concerned about
a relatively low sample size in this
initial work
thank you for this great question i also
saw one uh ask about the cliffhanger
effect i do want to give credit to both
joe hemley and natty weaver both the
co-developers of the program
and with regard to the low level of
participation i am at this moment not as
concerned
because of the timeline as you can see
we started around october 2020 and then
clearly covet uh during the during the
covet and then that's that's the
majority of our period of time so
both the cs mod children's hospital and
rogue cancer center were strictly shut
down which has impacted our recruitment
and just based on our actual recruitment
phase we were very pleased to see the
level of responses the clinical
referrals that we got so i'm not as
concerned about the the low number of um
inclusion and with regard to future
directions
um
i think the next step is really my dream
is to have a cancer specific storyline
and and i think the platform itself is
so powerful and the main character
doesn't have a cancer diagnosis and i
would hope that i would have a cancer
specific storyline and then
that platform would allow future teams
not just our team but future teams who
wanted to specialize for example in
prostate cancer to develop their own
story or breast cancer to develop their
own story which i think is highly
feasible
um and i think i answered all the
questions right
yeah absolutely thank you
i want to bring it back to dr hawkins as
we run out of time here there's a couple
of questions in the chat specifically
about what cbt looks like in some of
these interventions and any good
resources or recommendations you can
provide for folks to learn more and
actually anyone can answer i just wanted
to make sure that dr hawkins had an
opportunity to address her work as well
well thank you um i'll go ahead and let
someone else answer though um
we have uh cbt is something that i
um
am just beginning to work on and so
um i also want to say that
uh
like dr zhang and other folks um
who've been doing this work much longer
uh it would be
maybe a better idea for in terms of
resources that question i'm not sure
about to like washington county or
on
you know any of the other panelists feel
free to jump in and i want to specify it
did say t
cbt
okay yeah
so so i can chime in quickly um
my impression and i'm pretty sure
because cbt often is a um
in my view too widely utilized a a term
and so when i every time talk about cbt
specifically i would as i was
emphasizing the presentation it needs to
be adhered to the core components
because that we know that's what is the
most effective aspect of cbt so what it
looks like it it should at least in
principle in spirit and include those
three components i think a lot of the
variations in innovations comes to the
delivery of those core components into
the targeted population which i think
does require some
a lot more research with regard to
specific populations and with regard to
resources i think
there are a lot of entry-level even just
online
websites to start read about cbt the
academy of cognitive behavioral therapy
can be a good resources and the
association of cognitive behavior
therapy can be another good source to
start with
fantastic and i'll close out
the questions with you dr hawkins and
that is um
there's a question that says do you
think that having african-american men
participate by leading uh in providing
information and support is a strategy to
Keep more engaged
01:49:39
keep them more engaged or more fully
engaged
oh absolutely
um
you know the issue isn't necessarily um
i think there's a misconception that
um
the research sometimes perpetuates with
um african-american men with chronic
illnesses is that you know they're
they're not engaged in their care
they um
for whatever reason don't care about
taking care of themselves or going to
the doctor
when really they face real barriers uh
to
getting to the doctor in the first place
and participating in programs like this
so
absolutely getting them together it's
really wonderful to see
all of the amazing things that they
share how engaged they are and how they
support each other
the issue really
in
programs like these is
finding them in the first place
and then thinking about how we can
remove the barriers to get them to
stay in a program long term
and certainly one of those strategies is
to get them in a group with folks who
have similar experiences who are talking
about things that are relevant to them
what i will say is the traditional
diabetes self-management education
that's delivered by a certified diabetes
educator is typically in a
lecture style format
and
there's some ridiculous number folks go
to the first session and about ninety
percent of people don't come back
um and so we clearly need to
rethink how we're engaging folks
absolutely that's a great point do any
of the panelists have any final thoughts
before we turn it back over to emma
no
well thank you everyone and emma i'll
turn it back over to you
yeah i think joe might have a few
comments to close this out i'm gonna add
him to screen right now oops i didn't
that's okay but anyway uh just thanks to
everyone and to emma for organizing this
and uh
super excited to see all this amazing
work and
great talks inspirational work here at
the school of social work and
thanks to everyone for attending uh this
second in the series of three
talks on uh intervention research which
there's plenty of great stuff happening
here at the school so thanks so much for
attending
great thanks everyone we'll see you next
time
happy birthday school of social work
you